17β-HSD1-IN-1
17β-HSD1-IN-1 (Compound 1) is a highly selective 17β-HSD1 inhibitor with IC50s of 5.6 and 3155 nM for 17β-HSD1 and 17β-HSD2, respectively. 17β-HSD1-IN-1 can be used for the research of non-small cell lung cancer (NSCLC) [1].
Product Specifications
CAS Number
[2760791-96-4]
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/17β-hsd1-in-1.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=CC=C1N(C(C2=CC=C(O2)C3=CC(C)=C(C(C)=C3)O)=O)C
Molecular Formula
C21H21NO3
Molecular Weight
335.40
References & Citations
[1]Emanuele M Gargano, et al. 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibition: A Potential Treatment Option for Non-Small Cell Lung Cancer. ACS Med Chem Lett. 2021 Nov 18;12 (12) :1920-1924.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HINT1; KHK-A
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS4381610-01 0.02 mg (With BSA & Azide at 0.2mg/mL)
ZAP70(Chronic Lymphocytic Leukemia Marker)
Ask
View Details 
MBS4381610-02 0.1 mg (With BSA & Azide at 0.2mg/mL)
ZAP70(Chronic Lymphocytic Leukemia Marker)
Ask
View Details MBS4381610-03 0.1 mg (Without BSA & Azide at 1mg/mL)
ZAP70(Chronic Lymphocytic Leukemia Marker)
Ask
View Details MBS4381610-04 5x 0.1 mg (With BSA & Azide at 0.2mg/mL)
ZAP70(Chronic Lymphocytic Leukemia Marker)
Ask
View Details 
MBS4381610-05 5x 0.1 mg (Without BSA & Azide at 1mg/mL)
ZAP70(Chronic Lymphocytic Leukemia Marker)
Ask
View Details