What is the catalog number for Gracillin?

The catalog number for Gracillin is HY-N0706.

What sizes are available for Gracillin?

Gracillin is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Gracillin come in?

Gracillin is available in 6 different pack sizes.

Is Gracillin in stock?

Gracillin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Gracillin?

Gracillin is manufactured by QuantiMol.

What is the estimated delivery time for Gracillin?

Estimated delivery time for Gracillin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Gracillin?

The safety data sheet for Gracillin is available here: http://file.medchemexpress.com/batch_PDF/HY-N0706/Gracillin-SDS-MedChemExpress.pdf.

Gracillin

Gracillin is a steroidal saponin that can be extracted from the roots of the plant and has anti-tumor properties. Gracillin can induce cancer cell apoptosis and autophagy[1][2].

Product Specifications

CAS Number

19083-00-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy

Type

Natural Products

Related Pathways

Apoptosis; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Gracillin.html

Concentration

10mM

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])C[C@@]1([H])[C@@](CC=C5[C@@]6(CC[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)([H])[C@@H]7O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)C5)C)([H])[C@]6([H])CC2

Molecular Formula

C45H72O17

Molecular Weight

885.04

Precautions

H302, H315, H319, H335

References & Citations

[1]Min HY, et al. The natural compound gracillin exerts potent antitumor activity by targeting mitochondrial complex II. Cell Death Dis. 2019 Oct 24;10 (11) :810. |[2]Yang J, et al. Gracillin Isolated from Reineckia carnea Induces Apoptosis of A549 Cells via the Mitochondrial Pathway. Drug Des Devel Ther. 2021 Jan 20;15:233-243.|[3]Li Y, et al. Gracillin Shows Potential Efficacy Against Non-Small Cell Lung Cancer Through Inhibiting the mTOR Pathway. Front Oncol. 2022 Mar 22;12:851300.