GRIK2, Human (HEK293, hFc)

GRIK2 is an ionotropic glutamate receptor that plays an important role in central nervous system synapses, responding to L-glutamate as an excitatory neurotransmitter. Upon binding of L-glutamate, GRIK2 undergoes a conformational change that opens cation channels that convert chemical signals into electrical impulses. GRIK2 Protein, Human (HEK293, hFc) is the recombinant human-derived GRIK2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of GRIK2 Protein, Human (HEK293, hFc) is 530 a.a., with molecular weight of ~100-115 kDa.

TTHVLRFGGI FEYVESGPMG AEELAFRFAV NTINRNRTLL PNTTLTYDTQ KINLYDSFEA SKKACDQLSL GVAAIFGPSH SSSANAVQSI CNALGVPHIQ TRWKHQVSDN KDSFYVSLYP DFSSLSRAIL DLVQFFKWKT VTVVYDDSTG LIRLQELIKA PSRYNLRLKI RQLPADTKDA KPLLKEMKRG KEFHVIFDCS HEMAAGILKQ ALAMGMMTEY YHYIFTTLDL FALDVEPYRY SGVNMTGFRI LNTENTQVSS IIEKWSMERL QAPPKPDSGL LDGFMTTDAA LMYDAVHVVS VAVQQFPQMT VSSLQCNRHK PWRFGTRFMS LIKEAHWEGL TGRITFNKTN GLRTDFDLDV ISLKEEGLEK IGTWDPASGL NMTESQKGKP ANITDSLSNR SLIVTTILEE PYVLFKKSDK PLYGNDRFEG YCIDLLRELS TILGFTYEIR LVEDGKYGAQ DDANGQWNGM VRELIDHKAD LAVAPLAITY VREKVIDFSK PFMTLGISIL YRKPNGTNPG VFSFLNPLSP