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RGD

RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

Product Specifications

CAS Number

[99896-85-2]

UNSPSC

12352209

Hazard Statement

H315, H319, H335

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/RGD.html

Purity

99.60

Solubility

DMSO : 1.94 mg/mL (ultrasonic; adjust pH to 3 with HCl) |H2O : 10 mg/mL (ultrasonic)

Smiles

O=C(O)C[C@@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)N)=O)=O

Molecular Formula

C12H22N6O6

Molecular Weight

346.34

Precautions

H315, H319, H335

References & Citations

[1]Hersel U, et al. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials. 2003 Nov;24 (24) :4385-415.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Scientific Category

Peptides

Clinical Information

No Development Reported

Citation 01

BioRxiv. 2025 Aug 12.|Cancer Sci. 2020 May 24;111 (8) :2803-2813. |Int J Biol Macromol. 2023 Dec 31;253 (Pt 1) :126499.|Mater Sci Forum. 2019, 955: 68-73.|Nat Commun. 2024 Apr 18;15 (1) :3343.|Chem Eng J. 5 February 2022, 135088.|Colloid Polym Sci. 2023 Feb 27.

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