Elbanizine
Elbanizine inhibits histamine, bradykinin, histamin-release from rat mast cells (IC50 of 0.26 μM) and the IgE-mediated passive cutaneous anaphylaxis (PCA) reaction. Elbanizine exhibits antiallergic and antiasthmatic in guinea pig model[1].
Product Specifications
CAS Number
110629-41-9
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/elbanizine.html
Solubility
10 mM in DMSO
Smiles
O=[N+](C1=C(NCCN2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C=C(C)N=C1C)[O-]
Molecular Formula
C26H31N5O2
Molecular Weight
445.56
References & Citations
[1]Anagnostopulos H, et al., Synthesis of basic substituted pyridines: a new class of antiasthmatic-antiallergic agents[J]. European journal of medicinal chemistry, 1989, 24 (3) : 227-232.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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