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Elbanizine

Elbanizine inhibits histamine, bradykinin, histamin-release from rat mast cells (IC50 of 0.26 μM) and the IgE-mediated passive cutaneous anaphylaxis (PCA) reaction. Elbanizine exhibits antiallergic and antiasthmatic in guinea pig model[1].

Product Specifications

CAS Number

110629-41-9

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/elbanizine.html

Solubility

10 mM in DMSO

Smiles

O=[N+](C1=C(NCCN2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C=C(C)N=C1C)[O-]

Molecular Formula

C26H31N5O2

Molecular Weight

445.56

References & Citations

[1]Anagnostopulos H, et al., Synthesis of basic substituted pyridines: a new class of antiasthmatic-antiallergic agents[J]. European journal of medicinal chemistry, 1989, 24 (3) : 227-232.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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