Biotin HER-2 substrate peptide
Product Specifications
UNSPSC Description
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a Km value of 60 μm for Her2/neu kinase domain[1].
Target Antigen
EGFR
Type
Peptides
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-her-2-substrate-peptide.html
Smiles
O=C(NCC(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCSC)C(NCC(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CNC(CCCC[C@@H]4SC[C@]([C@]4([H])N5)([H])NC5=O)=O
Molecular Weight
2062.43
References & Citations
[1]John Monsey, et al. Her4 and Her2/neu Tyrosine Kinase Domains Dimerize and Activate in a Reconstituted in Vitro System. J Biol Chem. 2010 Mar 5; 285(10): 7035–7044.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10569/Biotin-HER-2-substrate-peptide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10569/
Clinical Information
No Development Reported
Curated Selection
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