Biotin HER-2 substrate peptide

Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a Km value of 60 μm for Her2/neu kinase domain[1].

Product Specifications

UNSPSC

12352209

Target

EGFR

Type

Peptides

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/biotin-her-2-substrate-peptide.html

Smiles

O=C(NCC(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCSC)C(NCC(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CNC(CCCC[C@@H]4SC[C@]([C@]4([H])N5)([H])NC5=O)=O

Molecular Formula

C93H140N22O25S3

Molecular Weight

2062.43

References & Citations

[1]John Monsey, et al. Her4 and Her2/neu Tyrosine Kinase Domains Dimerize and Activate in a Reconstituted in Vitro System. J Biol Chem. 2010 Mar 5; 285 (10) : 7035–7044.