N-Acetylglucosaminyltransferase IVa
Selected Variant
HY-E70297-01
Size: 1 mg
N-Acetylglucosaminyltransferase IVa (MGAT4A) is a glycosyltransferase that can enhance the migration, invasion, and adhesion abilities of cancer cells, and increase β1,4GlcNAc branched glycans on integrin β1 (ITGB1), a tumor-associated glycoprotein closely related to cell motility[1].
Product Specifications
Product Name Alternative
MGAT4A
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-acetylglucosaminyltransferase-iva.html
Solubility
10 mM in DMSO
Smiles
[N-AcetylglucosaminyltransferaseIVa]
References & Citations
[1]Yang D, et al. N-glycosylation by N-acetylglucosaminyltransferase IVa enhances the interaction of integrin β1 with vimentin and promotes hepatocellular carcinoma cell motility. Biochim Biophys Acta Mol Cell Res. 2023 Oct;1870 (7) :119513.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
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