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N-Acetylglucosaminyltransferase IVa

Selected Variant

HY-E70297-01

Size: 1 mg

N-Acetylglucosaminyltransferase IVa (MGAT4A) is a glycosyltransferase that can enhance the migration, invasion, and adhesion abilities of cancer cells, and increase β1,4GlcNAc branched glycans on integrin β1 (ITGB1), a tumor-associated glycoprotein closely related to cell motility[1].

Product Specifications

Product Name Alternative

MGAT4A

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-acetylglucosaminyltransferase-iva.html

Solubility

10 mM in DMSO

Smiles

[N-AcetylglucosaminyltransferaseIVa]

References & Citations

[1]Yang D, et al. N-glycosylation by N-acetylglucosaminyltransferase IVa enhances the interaction of integrin β1 with vimentin and promotes hepatocellular carcinoma cell motility. Biochim Biophys Acta Mol Cell Res. 2023 Oct;1870 (7) :119513.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Available Sizes

Price

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