Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Molidustat (sodium)

Molidustat sodium is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat sodium can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat sodium can be utilized in the research of renal anemia[1][2].

Product Specifications

CAS Number

1375799-59-9

UNSPSC

12352005

Hazard Statement

H317-H319-H360-H372

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/molidustat-sodium.html

Smiles

[Na]OC1=C(N2N=NC=C2)C=NN1C3=NC=NC(N4CCOCC4)=C3

Molecular Formula

C13H13N8NaO2

Molecular Weight

336.28

Precautions

P260-P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P362+P364-P405-P501

References & Citations

[1]Yamamoto H, et al. Molidustat for Renal Anemia in Nondialysis Patients Previously Treated with Erythropoiesis-Stimulating Agents: A Randomized, Open-Label, Phase 3 Study. Am J Nephrol. 2021;52 (10-11) :884-893.|[2]Flamme I, et al. Mimicking hypoxia to treat anemia: HIF-stabilizer BAY 85-3934 (Molidustat) stimulates erythropoietin production without hypertensive effects. PLoS One. 2014 Nov 13;9 (11) :e111838.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

O-Pentylresorufin
TRC-P284200-50MG 50 mg

O-Pentylresorufin

Sign In for Pricing
View Details
CD43 (T-Cell Marker) (rSPN/1094), CF594 conjugate, 0.1mg/mL
BNC941858-100 1x 100 µL

CD43 (T-Cell Marker) (rSPN/1094), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Recombinant MDH1 Antibody
RC-16696-01 50 μL

Recombinant MDH1 Antibody

Sign In for Pricing
View Details
Recombinant MDH1 Antibody
RC-16696-02 100 µL

Recombinant MDH1 Antibody

Sign In for Pricing
View Details
Recombinant MDH1 Antibody
RC-16696-03 1 mL

Recombinant MDH1 Antibody

Sign In for Pricing
View Details
Bromophos-ethyl
TRC-B686575-250MG 250 mg

Bromophos-ethyl

Sign In for Pricing
View Details