Phenosafranine

Phenosafranine is a phenazine dye. Phenosafranine has high binding affinity to triplex RNA compared to the parent duplex form, binds through intercalation to both forms of RNA. Phenosafranine can be used for staining plant cells, determination of hemoglobin, dopamine, serotonin and so on[1][2][3].

Product Specifications

CAS Number

[81-93-6]

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/phenosafranine.html

Purity

90.77

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

NC1=CC2=[N+](C3=C(N=C2C=C1)C=CC(N)=C3)C4=CC=CC=C4.[Cl-]

Molecular Formula

C18H15ClN4

Molecular Weight

322.80

Precautions

H315, H319, H335

References & Citations

[1]Widholm JM. The use of fluorescein diacetate and phenosafranine for determining viability of cultured plant cells. Stain Technol. 1972 Jul;47 (4) :189-94.|[2]Liu, W., et al. Characterization of Phenosafranine–Hemoglobin Interactions in Aqueous Solution. J Solution Chem 40, 231–246 (2011) .|[3]Pradhan AB, et al. An overview on the interaction of phenazinium dye phenosafranine to RNA triple and double helices. Int J Biol Macromol. 2016 May;86:345-51.