Crustacean cardioactive peptide, free acid

Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.

Product Specifications

CAS Number

[309247-84-5]

UNSPSC

12352209

Target

G Protein-coupled Receptor Kinase (GRK)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/crustacean-cardioactive-peptide-free-acid.html

Purity

99.38

Solubility

10 mM in H2O

Smiles

SC[C@@H](C(O)=O)NC(CNC([C@H]([C@H](O)C)NC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CS)NC([C@H](CC2=CC=CC=C2)NC([C@H]3NCCC3)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C42H58N10O12S2

Molecular Weight

959.10

References & Citations

[1]Suggs JM, et al. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. J Exp Biol. 2016 Aug 1;219 (Pt 15) :2388-95.|[2]Moris-Sanz M, et al. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015 Aug 14;4 (9) :1132-42.