SC5AC rabbit pAb

Normal blood lactate is maintained at about 1. 5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al. 2007 [PubMed 17692818]). [supplied by OMIM, Dec 2008],

Product Specifications

Background

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+) -coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+) -coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]) .[supplied by OMIM, Dec 2008]

UniProt

Q1EHB4

Swiss Prot

Q1EHB4

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human SC5AC AA range: 84-134

Target

SC5AC

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Apical cell membrane ; Multi-pass membrane protein . Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity) . .