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SC5AC rabbit pAb

Normal blood lactate is maintained at about 1. 5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al. 2007 [PubMed 17692818]). [supplied by OMIM, Dec 2008],

Product Specifications

Background

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+) -coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+) -coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]) .[supplied by OMIM, Dec 2008]

Gene ID

159963

UniProt

Q1EHB4

Cellular Locus

Apical cell membrane ; Multi-pass membrane protein. Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity)..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human SC5AC AA range: 84-134

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB

Validated Applications

WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1: 500-2000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES13190-1.pdf

Subcellular Location

Apical cell membrane ; Multi-pass membrane protein . Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity) . .

Gene ID (Human)

159963

SwissProt (Human)

Q1EHB4

Available Sizes

Curated Selection

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