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Lilial (Standard)

Lilial (Standard) is the analytical standard of Lilial. This product is intended for research and analytical applications. Lilial is a widely used synthetic fragrance and ester in consumer products. Lilial possesses estrogenic activity in vitro. Lilial can induce a toxic effect on mitochondria that causes a decrease in the viability of HaCaT cells. Lilial can increase NRF2 protein level in vitro. Lilial is able to target respiratory chain complexes, inhibit complexes I and II of the electron transport chain, increase the generation of reactive oxygen species, and decrease the level of intracellular ATP. Lilial can induce systemic toxicity in vivo. Lilial induces significant DNA strand breaks[1][2][3][4].

Product Specifications

CAS Number

80-54-6

UNSPSC

12352005

Hazard Statement

H227-H302-H315-H317-H361-H401-H412

Target

Keap1-Nrf2; Mitochondrial Metabolism; Reactive Oxygen Species (ROS) ; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/lilial-standard.html

Purity

96.55

Smiles

O=CC(C)CC1=CC=C(C(C)(C)C)C=C1

Molecular Formula

C14H20O

Molecular Weight

204.31

Precautions

P210-P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P370+P378-P403-P405-P501

References & Citations

[1]Arnau EG, et al. Identification of Lilial as a fragrance sensitizer in a perfume by bioassay-guided chemical fractionation and structure-activity relationships. Contact Dermatitis. 2000 Dec;43 (6) :351-8.|[2]Charles, A. K., & Darbre, P. D. (2009) . Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. Journal of applied toxicology : JAT, 29 (5), 422–434.|[3]Jablonská, E., et al., (2023) . Toxicological investigation of lilial. Scientific reports, 13 (1), 18536.|[4]Usta, J., et al., (2013) . Fragrance chemicals lyral and lilial decrease viability of HaCat cells' by increasing free radical production and lowering intracellular ATP level: protection by antioxidants. Toxicology in vitro : an international journal published in association with BIBRA, 27 (1), 339–348.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture, under nitrogen

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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