1-Hydroxyrutecarpine
1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity[1][2][3].
Product Specifications
CAS Number
53600-24-1
Product Name Alternative
1-Hydroxyrutaecarpine
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative
Type
Natural Products
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-hydroxyrutecarpine.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C(C(NC3=C4C=CC=C3)=C4CC2)=NC5=C1C=CC=C5O
Molecular Formula
C18H13N3O2
Molecular Weight
303.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bruno Danieli; et al. 1-Hydroxyrutaecarpine from Euxylophora paraënsis. Phytochemistry, 1974 , 13 (8), 1603–1606.|[2]Chen JJ, et al. New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum. Planta Med. 2005 May;71 (5) :470-5.|[3]Sheen WS, et al. Indolopyridoquinazoline alkaloids with antiplatelet aggregation activity from Zanthoxylum integrifoliolum. Planta Med. 1996 Apr;62 (2) :175-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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