6,7-Dimethylisatin
6,7-Dimethylisatin (compound 1l), an Isatin (HY-Y0265) analogue, is a potent MAO inhibitor with IC50s of 20.3 μM and 6.74 μM for MAO-A and MAO-B, respectively. 6,7-Dimethylisatin has the potential for depression, Alzheimer's disease and Parkinson's disease research[1].
Product Specifications
CAS Number
[20205-43-0]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/6-7-dimethylisatin.html
Smiles
O=C1NC2=C(C)C(C)=CC=C2C1=O
Molecular Formula
C10H9NO2
Molecular Weight
175.18
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Izak F Prinsloo, et al. The evaluation of isatin analogues as inhibitors of monoamine oxidase. Chem Biol Drug Des. 2023 Nov;102 (5) :1067-1074.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
