Rabdosin B
Rabdosin B is an ent-kaurene diterpenoid with anticancer effects. Rabdosin B induces DNA damage in cells, and inhibits lettuce root hair development of seedlings[1][2].
Product Specifications
CAS Number
[84304-92-7]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rabdosin-b.html
Solubility
10 mM in DMSO
Smiles
CC(OC[C@H](C1(C)C)[C@]([C@H](CC1)OC(C)=O)(COC2=O)[C@@]3([H])[C@]2(C(C4=C)=O)C[C@@]4([H])C[C@@H]3O)=O
Molecular Formula
C24H32O8
Molecular Weight
448.51
References & Citations
[1]Lan Ding, et al. Regulation of cell division and growth in roots of Lactuca sativa L. seedlings by the Ent-Kaurene diterpenoid rabdosin B. J Chem Ecol. 2010 May;36 (5) :553-63. |[2]Lan Ding, et al. Comparison of cytotoxicity and DNA damage potential induced by ent-kaurene diterpenoids from Isodon plant. Nat Prod Res. 2011 Sep;25 (15) :1402-11.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7229/Rabdosin-B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7229/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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