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2'-O,4'-C-Methyleneadenosine

2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].

Product Specifications

CAS Number

206055-70-1

Product Name Alternative

LNA-A

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-o-4-c-methyleneadenosine.html

Purity

97.23

Solubility

H2O : 11.11 mg/mL (ultrasonic)

Smiles

OC[C@]1(CO2)[C@@H](O)[C@@H]2[C@H](N3C(N=CN=C4N)=C4N=C3)O1

Molecular Formula

C11H13N5O4

Molecular Weight

279.26

Precautions

H315, H319, H335

References & Citations

[1]Ravn J, et al. Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15 (16) :5440-7.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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