2'-O,4'-C-Methyleneadenosine
2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].
Product Specifications
CAS Number
[206055-70-1]
Product Name Alternative
LNA-A
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-o-4-c-methyleneadenosine.html
Purity
97.23
Solubility
H2O : 11.11 mg/mL (ultrasonic)
Smiles
OC[C@]1(CO2)[C@@H](O)[C@@H]2[C@H](N3C(N=CN=C4N)=C4N=C3)O1
Molecular Formula
C11H13N5O4
Molecular Weight
279.26
Precautions
H315, H319, H335
References & Citations
[1]Ravn J, et al. Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15 (16) :5440-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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