QL47R
QL47R is an approximately isosteric analogue of QL47. QL47R dose not inhibit the biochemical kinase activity of BTK at concentrations below 10 μM. QL47R dose not display antiproliferative activity on B-Cell Lymphoma Cell Lines at concentrations of less than 10 μM[1].
Product Specifications
CAS Number
1579278-89-9
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ql47r.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=CN=C3C=CC(C4=CN(C)N=C4)=CC3=C2N1C5=CC=C6C(N(CC6)C(CC)=O)=C5
Molecular Formula
C27H23N5O2
Molecular Weight
449.50
References & Citations
[1]Wu H, et al. Discovery of a potent, covalent BTK inhibitor for B-cell lymphoma. ACS Chem Biol. 2014 May 16;9 (5) :1086-91.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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