Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DHFR-IN-17

DHFR-IN-17 (compound j9) is an oral active SaDHFR inhibitor with the IC50 of 0.97 nM. DHFR-IN-17 shows antibacterial activity against S. aureus with the minimum inhibitory concentration of 0.031 μg/mL[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial; Dihydrofolate reductase (DHFR)

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dhfr-in-17.html

Solubility

10 mM in DMSO

Smiles

CC(C1=C(C=C(C(OCC2CC2)=C1)I)OC3=CN=C(N=C3N)N)C

Molecular Formula

C17H21IN4O2

Molecular Weight

440.28

References & Citations

[1]Huang Z, et al. Design, Synthesis, and Biological Evaluation of 5- (5-Iodo-2-isopropyl-4-methoxyphenoxy) pyrimidine-2,4-diamine (AF-353) Derivatives as Novel DHFR Inhibitors against Staphylococcus aureus. J Med Chem. Published online March 11, 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Cyhalothrin
TRC-C989918-1G 1 g

Cyhalothrin

Sign In for Pricing
View Details
Fenbuconazole-lactone A R-9129
TRC-T767725-5MG 5 mg

Fenbuconazole-lactone A R-9129

Sign In for Pricing
View Details
Ccdc141 Mouse Gene Knockout Kit (CRISPR)
KN502661 1 Kit

Ccdc141 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
PTOP (ACD) (NM_001082487) Human Over-expression Lysate
LC421184 20 µg

PTOP (ACD) (NM_001082487) Human Over-expression Lysate

Sign In for Pricing
View Details
FHIT Mouse Monoclonal Antibody [Clone ID: OTI2C1]
CF811502 100 µg

FHIT Mouse Monoclonal Antibody [Clone ID: OTI2C1]

Sign In for Pricing
View Details
Tissue FFPE Sections, Brain
CS805790 5x 5 µm

Tissue FFPE Sections, Brain

Sign In for Pricing
View Details