7-Amino-4-methylcoumarin

7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.[1][2][3][4]

Product Specifications

CAS Number

[26093-31-2]

Product Name Alternative

Coumarin 120; AMC

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Fluorescent Dye; Fungal

Type

Dye Reagents

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/7-Amino-4-methylcoumarin.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C(C)C2=CC=C(N)C=C2O1

Molecular Formula

C10H9NO2

Molecular Weight

175.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Żamojć K, et al. Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt C:1875-80. |[2]Hiroshi Takase, et al. 7-Amino-4-methylcoumarin as a fluorescent substitute for Schiff's reagent: a new method that can be combined with hemalum and eosin staining on the same tissue section. Biotech Histochem. 2023 Jan;98 (1) :54-61.|[3]M. Goodfellow, et al. Characterisation of rhodococci using peptide hydrolase substrates based on 7-amino-4-methylcoumarin. FEMS Microbiology Letters,1987 Nov; 44 (3) : 349-355.|[4]Xiaoyan Sun, wt al. A highly sensitive and selective ratiometric sensing platform based on 7-amino-4-methylcoumarin for naked-eye visual fluorescence sensing of Cu2. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Feb 15;267 (Pt 2) :120627.