Sulfuretin

Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].

Product Specifications

CAS Number

[120-05-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sulfuretin.html

Purity

99.36

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1/C(OC2=CC(O)=CC=C12)=C/C3=CC=C(O)C(O)=C3

Molecular Formula

C15H10O5

Molecular Weight

270.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Mi-Young Song, et al. Sulfuretin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 10;400 (1) :83-8.|[2]Chen, H., et al. Isolation of sulfuretin and butin from Rhus verniciflua Stokes using medium-pressure liquid chromatography and their tyrosinase inhibitory effects. BioRes. 11 (1), 759-771.