LY2562175
LY2562175 is a potent and selective FXR agonist, with an EC50 of 193 nM[1].
Product Specifications
CAS Number
1103500-20-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Autophagy; FXR
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/LY2562175.html
Purity
99.49
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(C)C2=C1C=CC(N3CCC(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)CC3)=C2)O
Molecular Formula
C28H27Cl2N3O4
Molecular Weight
540.44
Precautions
H302, H315, H319
References & Citations
[1]Genin MJ, et al. Discovery of 6- (4-{[5-Cyclopropyl-3- (2,6-dichlorophenyl) isoxazol-4-yl]methoxy}piperidin-1-yl) -1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia. J Med Chem. 2015 Dec 24;58 (24) :9768-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC400190 20 µg
hemoglobin subunit gamma 1 (HBG1) (NM_000559) Human Over-expression Lysate
Sign In for Pricing
View Details 
