Ceramides Mixture

Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity[1][2].

Product Specifications

CAS Number

[100403-19-8]

Product Name Alternative

MK-0822-d12

UNSPSC

12352005

Hazard Statement

H319

Target

Telomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ceramides-mixture.html

Purity

99.8

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[CeramidesMixture]

Precautions

H319

References & Citations

[1]Ogretmen B, et al. Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. Role for endogenous ceramide in mediating the action of exogenous ceramide. J Biol Chem. 2002 Apr 12;277 (15) :12960-9.|[2]Macheleidt O, et al. Deficiency of epidermal protein-bound omega-hydroxyceramides in atopic dermatitis. J Invest Dermatol. 2002 Jul;119 (1) :166-73.