What is the catalog number for Deracoxib?

The catalog number for Deracoxib is HY-17509.

What sizes are available for Deracoxib?

Deracoxib is available in the following size(s): 25 mg, 10 mM - 1 mL, 50 mg, 100 mg, 500 mg, 1 g.

How many pack sizes does Deracoxib come in?

Deracoxib is available in 6 different pack sizes.

Is Deracoxib in stock?

Deracoxib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Deracoxib?

Deracoxib is manufactured by QuantiMol.

What is the estimated delivery time for Deracoxib?

Estimated delivery time for Deracoxib is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Deracoxib?

The safety data sheet for Deracoxib is available here: http://file.medchemexpress.com/batch_PDF/HY-17509/Deracoxib-SDS-MedChemExpress.pdf.

Deracoxib

Deracoxib (SC 046; SC 59046), an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas[1][2][3][4][5].

Product Specifications

CAS Number

169590-41-4

Product Name Alternative

SC 046; SC 46; SC 59046

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; COX

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/deracoxib.html

Purity

99.65

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(N2N=C(C(F)F)C=C2C3=CC=C(OC)C(F)=C3)C=C1)(N)=O

Molecular Formula

C17H14F3N3O3S

Molecular Weight

397.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Royals, S.R., et al., Investigation of the effects of deracoxib and piroxicam on the in vitro viability of osteosarcoma cells from dogs. Am J Vet Res, 2005. 66 (11) : p. 1961-7.|[2]Ustun Alkan, F., et al., The effects of piroxicam and deracoxib on canine mammary tumour cell line. ScientificWorldJournal, 2012. 2012: p. 976740.|[3]Bienhoff, S.E., et al., Efficacy and safety of deracoxib for control of postoperative pain and inflammation associated with soft tissue surgery in dogs. Vet Surg, 2012. 41 (3) : p. 336-44.|[4]McMillan, S.K., et al., Antitumor effects of deracoxib treatment in 26 dogs with transitional cell carcinoma of the urinary bladder. J Am Vet Med Assoc, 2011. 239 (8) : p. 1084-9.|[5]Anderson GD, et al. Combination therapies that inhibit cyclooxygenase-2 and leukotriene synthesis prevent disease in murine collagen induced arthritis. Inflamm Res. 2009 Feb;58 (2) :109-17.