Rofleponide
Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models[1].
Product Specifications
CAS Number
144459-70-1
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/rofleponide.html
Solubility
10 mM in DMSO
Smiles
OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(CC5)=O)C)F)([H])C[C@@]1([H])O[C@H](O2)CCC)C)=O
Molecular Formula
C25H34F2O6
Molecular Weight
468.53
References & Citations
[1]Thalén A, et al. Synthesis and structure elucidation of potential 6-oxygenated metabolites of (22R) -6α, 9α-difluoro-11β, 21-dihydroxy-16α, 17α-propylmethylenedioxypregn-4-ene-3, 20-dione, and related glucocorticosteroids[J]. Steroids, 2000, 65 (1) : 16-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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