XMD16-5
XMD16-5 is a potent TNK2 inhibitor with IC50 values of 16 and 77 nM for the D163E and R806Q mutations, respectively.
Product Specifications
CAS Number
1345098-78-3
UNSPSC
12352005
Hazard Statement
H302
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/XMD16-5.html
Purity
98.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=CN=C(NC3=CC=C(N4CCC(O)CC4)C=C3)N=C2N(C)C5=CC=CC=C15
Molecular Formula
C23H24N6O2
Molecular Weight
416.48
Precautions
H302
References & Citations
[1]Maxson JE, et al. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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