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XMD16-5

XMD16-5 is a potent TNK2 inhibitor with IC50 values of 16 and 77 nM for the D163E and R806Q mutations, respectively.

Product Specifications

CAS Number

1345098-78-3

UNSPSC

12352005

Hazard Statement

H302

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/XMD16-5.html

Purity

98.20

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC2=CN=C(NC3=CC=C(N4CCC(O)CC4)C=C3)N=C2N(C)C5=CC=CC=C15

Molecular Formula

C23H24N6O2

Molecular Weight

416.48

Precautions

H302

References & Citations

[1]Maxson JE, et al. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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