NTPO (trisodium)
Product Specifications
UNSPSC Description
NTPO trisodium is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO trisodium are abrogated by base excision repair (BER) but not nucleotide excision repair (NER)[1].
Target Antigen
Others
Type
Biochemical Assay Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/ntpo-trisodium.html
Solubility
10 mM in DMSO
Smiles
O=P(CN(CP(O)(O[Na])=O)CP(O)(O[Na])=O)(O[Na])O
Molecular Weight
365.00
References & Citations
[1]Choi JY, et al. Non-thermal plasma-induced apoptosis is modulated by ATR- and PARP1-mediated DNA damage responses and circadian clock. Oncotarget. 2016 May 31;7(22):32980-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W011425A/NTPO-trisodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W011425A/
Clinical Information
No Development Reported
CAS Number
7611-50-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6165053-01 0.1 mL
BNIP3L (BCL2/Adenovirus E1B 19kD Interacting Protein 3-like, BNIP3a, NIX) (AP)
Ask
View Details 
MBS6165053-02 5x 0.1 mL
BNIP3L (BCL2/Adenovirus E1B 19kD Interacting Protein 3-like, BNIP3a, NIX) (AP)
Ask
View Details 