2H-Cho-Arg (TFA)

2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

Product Specifications

CAS Number

[1609010-59-4]

UNSPSC

12352200

Hazard Statement

H225, H319

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2h-cho-arg-tfa.html

Concentration

11.29 mM * 500 μL in Ethanol

Purity

99.0

Smiles

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@@H](OC(CCCCCNC([C@@H](N)CCCNC(N)=N)=O)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

Molecular Formula

C43H73F6N5O7

Molecular Weight

886.06

Precautions

H225, H319

References & Citations

[1]Sheng R, Wang Z, Luo T, Cao A, Sun J, Kinsella JM. Skeleton-Controlled pDNA Delivery of Renewable Steroid-Based Cationic Lipids, the Endocytosis Pathway Analysis and Intracellular Localization. Int J Mol Sci. 2018;19 (2) :369.