Purified Anti-Human CD86 Antibody[IT2.2]
Product Specifications
Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Abbreviation
CD86
Gene ID
942
UniProt
P42081
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD86 protein
Target
LAB; ETC; FUN; CTLA-4 Counter-Receptor B; Early T-cell costimulatory molecule; CD28LG; B7-2; B7.2; B70; CD28LG2; LAB72; CD86; Activation B7-2 antigen; BU63; CTLA-4 Counter-Receptor B7.2; Early T-cell costimulatory molecule 1; ETC-1; FUN-1; T-lymphocyte activation antigen CD86; B7-2; Activation B7-2 antigen 3; B7 2; B72 antigen; B-lymphocyte activation antigen B7-2; B-lymphocyte activation antigen B7-2 2; CD28 antigen ligand 2; CD28 antigen ligand 2 2; Cd28l2; CD86 antigen; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2 2; FUN 1; Ly58; Ly-58; MB7; MB7-2; Membrane glycoprotein; MGC34413; TS/A-2
Clonality
Monoclonal
Clone
IT2.2
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Microbiology; Stem Cells; Kits; Lysates; Other
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/ve18lp
Product MSDS
https://789.bio/eb/tmy1xH
Isotype
Mouse IgG2b, κ
Available Sizes
Curated Selection
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