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CIL62

CIL62 is a caspase-3/7-independent cell death inducer. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death[1].

Product Specifications

CAS Number

[117593-36-9]

UNSPSC

12352005

Hazard Statement

H302

Target

Necroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cil62.html

Concentration

10mM

Purity

97.0

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1C(C(C2=CC=C(O)C=C2O)C3=C(CC(C)(C)CC3=O)O4)=C4CC(C)(C)C1

Molecular Formula

C23H26O5

Molecular Weight

382.45

Precautions

H302

References & Citations

[1]Kenichi Shimada, et al. Global Survey of Cell Death Mechanisms Reveals Metabolic Regulation of Ferroptosis. Nat Chem Biol. 2016 Jul;12 (7) :497-503.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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