Topoisomerase inhibitor 4
Selected Variant
HY-169106
Size: 1 Each
Topoisomerase inhibitor 4 (compound 45) is a potent Topoisomerase1/2 inhibitor. Topoisomerase inhibitor 4 causes cell cycle arrest in the G2/M phase by inducing Apoptosis. Topoisomerase inhibitor 4 has antitumor activity[1].
Product Specifications
CAS Number
3021532-95-3
UNSPSC
12352005
Target
Apoptosis; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-inhibitor-4.html
Smiles
C[N+](CCC(OC1=CC=C2NC3=C(C2=C1)CCN4C(C5=C(N(C34)C6=CC=CC(F)=C6)C(F)=CC(F)=C5)=O)=O)(C)C.[I-]
Molecular Formula
C30H28F3IN4O3
Molecular Weight
676.47
References & Citations
[1]Wei X, et al. Identification of a novel 10-hydroxyevodiamine prodrug as a potent topoisomerase inhibitor with improved aqueous solubility for treatment of hepatocellular carcinoma. Eur J Med Chem. 2024 Sep 1;279:116807.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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