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GABA A Receptor γ2 rabbit pAb

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

UniProt

P18507

Swiss Prot

P18507

Reactivity

Human; Rat; Mouse

Immunogen

Synthetic Peptide of GABA A Receptor γ2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF

Concentration

1 mg/ml

Dilution

WB 1:1000-2000, IHC 1:100-200

Molecular Weight

55kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

55kD

Fragment

IgG

Subcellular Location

Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cytoplasmic vesicle membrane .

Other Product Names

Gamma-aminobutyric acid receptor subunit gamma-2 (GABA (A) receptor subunit gamma-2)

Gene ID (Human)

2566

Available Sizes

Curated Selection

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