SARS-CoV-2 nsp13-IN-1
Product Specifications
UNSPSC Description
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research[1].
Target Antigen
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-nsp13-in-1.html
Solubility
DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC1=NC2=NC=CC=C2C(N1C3=CC=C(C=C3)NC(C4=CC=C(C=C4)C5=CC=CC=C5)=O)=O
Molecular Weight
432.47
References & Citations
[1]Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150622/SARS-CoV-2-nsp13-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150622/SARS-CoV-2-nsp13-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1005304-44-8
Available Sizes
Curated Selection
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