SARS-CoV-2 nsp13-IN-1
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research[1].
Product Specifications
CAS Number
[1005304-44-8]
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-nsp13-in-1.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=NC2=NC=CC=C2C(N1C3=CC=C(C=C3)NC(C4=CC=C(C=C4)C5=CC=CC=C5)=O)=O
Molecular Formula
C27H20N4O2
Molecular Weight
432.47
References & Citations
[1]Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0387705 3x 1.0 µg
CCDC158 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details 
RDR-NR3C1-Hu-48Tests 48 Tests
Human Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
Sign In for Pricing
View Details 37769156 3x 1.0 µg DNA
PRPH CRISPR All-in-one AAV vector set (with saCas9)(Rat)
Sign In for Pricing
View Details bs-9940R-PE-Cy5.5 100 µL
C11orf65 Polyclonal Antibody, PE-Cy5.5 Conjugated
Sign In for Pricing
View Details bsm-62853R-BF680 100 µL
Phospho-eIF4EBP1/2/3 (Thr46/Thr46/Thr32) Recombinant Antibody, AbBy Fluor™ 680 Conjugated
Sign In for Pricing
View Details bsm-61295R-APC-Cy7 100 µL
IKK alpha Recombinant Antibody, APC-Cy7 Conjugated
Sign In for Pricing
View Details