AR-A014418-d3
AR-A014418-d3 is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM) [1].
Product Specifications
CAS Number
1216908-63-2
Product Name Alternative
AR 0133418-d3; GSK 3β inhibitor VIII-d3; AR 014418-d3
UNSPSC
12352005
Target
GSK-3; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=C(OC([2H])([2H])[2H])C=C1)NC2=NC=C([N+]([O-])=O)S2
Molecular Formula
C12H9D3N4O4S
Molecular Weight
311.33
References & Citations
[1]Bhat R, Xue Y, Berg S, Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem. 2003 Nov 14;278 (46) :45937-45.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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