Midodrine-d6 (hydrochloride)

Midodrine-d6 (hydrochloride) is a selective and orally active adrenergic α1-receptor agonist. Midodrine-d6 (hydrochloride) can strengthen vascular contraction. Midodrine-d6 (hydrochloride) can be used for the researches of cardiovascular disease, such as orthostatic hypotension[1][2][3].

Product Specifications

CAS Number

[1188265-43-1]

UNSPSC

12352005

Hazard Statement

H301

Target

Adrenergic Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Purity

99.44

Solubility

10 mM in DMSO|H2O : 100mg/mL (ultrasonic)

Smiles

OC(CNC(CN)=O)C1=CC(OC([2H])([2H])[2H])=CC=C1OC([2H])([2H])[2H].[H]Cl

Molecular Formula

C12H13D6ClN2O4

Molecular Weight

296.78

Precautions

H301

References & Citations

[1]Criscuoli M, et al. Catecholamines released from the adrenal medulla exert a compensatory, protective effect at beta 2-adrenoceptors against Paf-induced death in mice. Br J Pharmacol. 1988 Jan;93 (1) :132-8.|[2]Inchan A, et al. Anti-hypotensive effect of "Yahom Navakot" in rats with orthostatic hypotension. J Tradit Complement Med. 2021 Aug 3;12 (2) :180-189.|[3]Lee YJ, et al. Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ. PPAR Res. 2020 Feb 1;2020:3785137.