N-dodecanoyl-L-Homoserine lactone

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1].

Product Specifications

CAS Number

[137173-46-7]

Product Name Alternative

C12-HSL

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/n-dodecanoyl-l-homoserine-lactone.html

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCC(N[C@H]1CCOC1=O)=O

Molecular Formula

C16H29NO3

Molecular Weight

283.41

Precautions

H315, H319, H335

References & Citations

[1]Borges A, et al. Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes. Biofouling. 2017 Feb;33 (2) :156-168.