S33084

S33084 is a dopamine D (3) -receptor antagonist with the pKi values of 8.72, 8.62 and 6.82 of cloned rat dopamine D3 receptor, native rat dopamine D3 and D2 receptor[1].

Product Specifications

CAS Number

[273203-30-8]

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s33084.html

Smiles

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NCCCCN3C[C@]4([H])C5=CC(C#N)=CC=C5OC[C@@]4([H])C3

Molecular Formula

C29H29N3O2

Molecular Weight

451.56

References & Citations

[1]Cussac D, et al. The novel antagonist, S33084, and GR218,231 interact selectively with cloned and native, rat dopamine D (3) receptors as compared with native, rat dopamine D (2) receptors. Eur J Pharmacol. 2000;394 (1) :47-50.