CC-90003
Product Specifications
UNSPSC Description
CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.
Target Antigen
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CC-90003.html
Purity
99.71
Solubility
DMSO : ≥ 125 mg/mL
Smiles
C=CC(NC1=CC(C)=CC=C1NC2=NC(NC3=CC(OC)=NC=C3C)=NC=C2C(F)(F)F)=O
Molecular Weight
458.44
References & Citations
[1]Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112570/CC-90003-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112570/CC-90003-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
1621999-82-3
Available Sizes
Curated Selection
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