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BCRP-IN-1

BCRP-IN-1 (compound 48) is a potent inhibitor of breast cancer resistance protein (BCRP), with IC50s of 2.92 μM and 2.46 μM in Hoechst 33342 assay and Pheophorbide A assay, respectively[1].

Product Specifications

CAS Number

765899-28-3

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

BCRP

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bcrp-in-1-1.html

Smiles

O=[N+](C1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1)[O-]

Molecular Formula

C16H14N4O4

Molecular Weight

326.31

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]"Kapil Juvale, et al. Investigation of quinazolines as inhibitors of breast cancer resistance protein (ABCG2) . Bioorg Med Chem. 2013 Dec 15;21 (24) :7858-73. "

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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