N-Lauroylsarcosine

N-lauroylsarcosine is an anionic surfactant. N-lauroylsarcosine has antiviral activity against HSV-2 strain 333 and HSV-1 strain F. N-lauroylsarcosine synergistically increases skin permeability with 25-50% ethanol. N-lauroylsarcosine can be used to study HSV-2 infection[1][2][3][4].

Product Specifications

CAS Number

[97-78-9]

UNSPSC

12352209

Hazard Statement

H315, H318, H330

Target

Biochemical Assay Reagents; HSV

Type

Peptides

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/n-lauroylsarcosine.html

Purity

99.81

Solubility

DMSO : ≥ 200 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCC(=O)N(C)CC(=O)O

Molecular Formula

C15H29NO3

Molecular Weight

271.40

Precautions

H315, H318, H330

References & Citations

[1]Roy S, et al. Thermoreversible gel formulations containing sodium lauryl sulfate or n-Lauroylsarcosine as potential topical microbicides against sexually transmitted diseases. Antimicrob Agents Chemother. 2001 Jun;45 (6) :1671-81.|[2]Piret J, et al. Comparative study of mechanisms of herpes simplex virus inactivation by sodium lauryl sulfate and n-lauroylsarcosine. Antimicrob Agents Chemother. 2002 Sep;46 (9) :2933-42.|[3]Kim YC, et al. Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol. Int J Pharm. 2008 Mar 20;352 (1-2) :129-38.|[4]Ishibashi T, et al. Contrasting effects of SM-9018, a potential atypical antipsychotic, and haloperidol on c-fos mRNA expression in the rat striatum. Eur J Pharmacol. 1996 May 15;303 (3) :247-51.