N-Lauroylsarcosine
N-lauroylsarcosine is an anionic surfactant. N-lauroylsarcosine has antiviral activity against HSV-2 strain 333 and HSV-1 strain F. N-lauroylsarcosine synergistically increases skin permeability with 25-50% ethanol. N-lauroylsarcosine can be used to study HSV-2 infection[1][2][3][4].
Product Specifications
CAS Number
97-78-9
UNSPSC
12352209
Hazard Statement
H315, H318, H330
Target
Biochemical Assay Reagents; HSV
Type
Peptides
Related Pathways
Anti-infection; Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/n-lauroylsarcosine.html
Purity
99.81
Solubility
DMSO : ≥ 200 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCC(=O)N(C)CC(=O)O
Molecular Formula
C15H29NO3
Molecular Weight
271.40
Precautions
H315, H318, H330
References & Citations
[1]Roy S, et al. Thermoreversible gel formulations containing sodium lauryl sulfate or n-Lauroylsarcosine as potential topical microbicides against sexually transmitted diseases. Antimicrob Agents Chemother. 2001 Jun;45 (6) :1671-81.|[2]Piret J, et al. Comparative study of mechanisms of herpes simplex virus inactivation by sodium lauryl sulfate and n-lauroylsarcosine. Antimicrob Agents Chemother. 2002 Sep;46 (9) :2933-42.|[3]Kim YC, et al. Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol. Int J Pharm. 2008 Mar 20;352 (1-2) :129-38.|[4]Ishibashi T, et al. Contrasting effects of SM-9018, a potential atypical antipsychotic, and haloperidol on c-fos mRNA expression in the rat striatum. Eur J Pharmacol. 1996 May 15;303 (3) :247-51.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
HSV-1; HSV-2
Available Sizes
Frequently Asked Questions
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