Mal-PEG3-C1-NHS ester
Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2230016-26-7]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg3-c1-nhs-ester.html
Concentration
260.19 mM * 100 μL in DMSO
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)COCCOCCOCCN2C(C=CC2=O)=O
Molecular Formula
C16H20N2O9
Molecular Weight
384.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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