Frizzled-4/CD344, Human (HEK293, His)
Product Specifications
UNSPSC Description
The Frizzled-4/CD344 protein is a receptor for Wnt proteins and is associated with the classical β-catenin pathway, activating disheveled proteins, inhibiting GSK-3 kinase, and triggering Wnt target genes. In retinal vascularization, it acts as a receptor for Wnt proteins and Norrin (NDP), stimulating β-catenin accumulation and LEF/TCF-mediated transcription. Frizzled-4/CD344 Protein, Human (HEK293, His) is the recombinant human-derived Frizzled-4/CD344 protein, expressed by HEK293 , with C-His labeled tag. The total length of Frizzled-4/CD344 Protein, Human (HEK293, His) is 144 a.a., with molecular weight of ~22-25 kDa.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/frizzled-4-cd344-protein-human-hek293-his.html
Purity
98.00
Smiles
FGDEEERRCD PIRISMCQNL GYNVTKMPNL VGHELQTDAE LQLTTFTPLI QYGCSSQLQF FLCSVYVPMC TEKINIPIGP CGGMCLSVKR RCEPVLKEFG FAWPESLNCS KFPPQNDHNH MCMEGPGDEE VPLPHKTPIQ PGEE
Molecular Weight
Approximately 22-25 kDa due to glycosylation
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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