COX-2-IN-47

COX-2-IN-47 (compound 6c) is a selective COX-2 inhibitor with IC50 value of 0.03 μM. COX-2-IN-47 has antiedema activity[1].

Product Specifications

CAS Number

[2043670-02-4]

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cox-2-in-47.html

Smiles

O=C(O)COC1=CC=C(C2=NNC(C3=CC=C(OC)C=C3)C2)C=C1

Molecular Formula

C18H18N2O4

Molecular Weight

326.35

References & Citations

[1]Elgohary MK, et al. Novel anti-inflammatory agents featuring phenoxy acetic acid moiety as a pharmacophore for selective COX-2 inhibitors: Synthesis, biological evaluation, histopathological examination and molecular modeling investigation. Bioorg Chem. 2024 Nov;152:107727.