COX-2-IN-47
COX-2-IN-47 (compound 6c) is a selective COX-2 inhibitor with IC50 value of 0.03 μM. COX-2-IN-47 has antiedema activity[1].
Product Specifications
CAS Number
[2043670-02-4]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-47.html
Smiles
O=C(O)COC1=CC=C(C2=NNC(C3=CC=C(OC)C=C3)C2)C=C1
Molecular Formula
C18H18N2O4
Molecular Weight
326.35
References & Citations
[1]Elgohary MK, et al. Novel anti-inflammatory agents featuring phenoxy acetic acid moiety as a pharmacophore for selective COX-2 inhibitors: Synthesis, biological evaluation, histopathological examination and molecular modeling investigation. Bioorg Chem. 2024 Nov;152:107727.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
Curated Selection
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