Filipin II
Filipin II is an antibiotic, which exhibits antifungal efficacy. Filipin II interacts with membrane sterols, leads to changes in membrane structure, inhibits Candida utilis and Saccharomyces cerevisiae with the MIC of 0.03 mg/L and 0.2 μg/L[1][2].
Product Specifications
CAS Number
[38620-77-8]
UNSPSC
12352211
Target
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/filipin-ii.html
Smiles
O=C1O[C@H](C)[C@@H](O)/C=C/C=C/C=C/C=C/C=C(C)/[C@@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)[C@H]1CCCCCC
Molecular Formula
C35H58O10
Molecular Weight
638.83
References & Citations
[1]Payero TD, et al., Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives. Microb Cell Fact. 2015 Aug 7;14:114.|[2]Gao H, et al. Filipins: the first antifungal “weed killers” identified from bacteria isolated from the trap-ant[J]. Rsc Advances, 2014, 4 (100) : 57267-57270.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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