Filipin II
Product Specifications
UNSPSC Description
Filipin II is an antibiotic, which exhibits antifungal efficacy. Filipin II interacts with membrane sterols, leads to changes in membrane structure, inhibits Candida utilis and Saccharomyces cerevisiae with the MIC of 0.03 mg/L and 0.2 μg/L[1][2].
Target Antigen
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/filipin-ii.html
Smiles
O=C1O[C@H](C)[C@@H](O)/C=C/C=C/C=C/C=C/C=C(C)/[C@@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)[C@H]1CCCCCC
Molecular Weight
638.83
References & Citations
[1]Payero TD, et al., Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives. Microb Cell Fact. 2015 Aug 7;14:114.|[2]Gao H, et al. Filipins: the first antifungal “weed killers” identified from bacteria isolated from the trap-ant[J]. Rsc Advances, 2014, 4(100): 57267-57270.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130772/Filipin-II-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130772/
Clinical Information
No Development Reported
CAS Number
38620-77-8
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