L-Aspartic acid-13C4

L-Aspartic acid-13C4 is the 13C-labeled L-Aspartic acid. L-Aspartic aicd is an amino acid that can penetrate the blood-brain barrier. L-Aspartic aicd is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd commonly used in the study of inflammatory conditions[1][2][3].

Product Specifications

CAS Number

[55443-54-4]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-aspartic-acid-13c4.html

Purity

99.65

Solubility

1 M NaOH : 100 mg/mL (adjust pH to 12 with 1 M NaOH)

Smiles

O[13C]([13C@](N)([H])[13C]([H])([H])[13C](O)=O)=O

Molecular Formula

13C4H7NO4

Molecular Weight

137.07

References & Citations

[1]Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly (L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23 (4) :397-406. |[2]Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73 (3) :1206-11. |[3]Su G, et al. Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub. Redox Biol. 2024 May;71:103112.