D-Val-Leu-Arg-pNA

D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin[1].

Product Specifications

CAS Number

[64816-14-4]

UNSPSC

12352209

Hazard Statement

H302-H315-H319-H335

Target

PAI-1

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/d-val-leu-arg-pna.html

Solubility

10 mM in DMSO

Smiles

CC(C)[C@@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)=O)=O

Molecular Formula

C23H38N8O5

Molecular Weight

506.60

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Fischer BE, et al. Effects of intact fibrin and partially plasmin-degraded fibrin on kinetic properties of one-chain tissue-type plasminogen activator. Biochim Biophys Acta. 1990 Oct 18;1041 (1) :48-54.